"Science is more than the body of knowledge, its a way of thinking, a way of skeptically interrogating the universe" -Carl Sagan
3D protein structure |
The three dimensional structure of a protein is determined by its sequence, and the function of a protein is determined by its three dimensional structure.
Four levels of structure.
- Primary - Amino acids sequence, are covalently link (Peptide bonds) and any disulphide bridge are included in the primary structure. The following protein structures are dependent upon non covalent interactions.
- Secondary - Regular reoccurring arrangement that occurs within adjacent amino acids. Which are:
- Alpha helix
- Beta pleated sheet
- Tertiary - Spatial relationship between all peptides in a protein. Protein folding brings sequentially distance close together. Fibrous, long strands or sheets, structural proteins with a single secondary type of secondary structure.Globular, spherical; complex structures with many types of secondary structure. Enzymes and olypeptide hormones are usually globular peptides.
- Quaternary - Arrangement of polypeptide change ( sub units ) within a protein.
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